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Omran Abu Aboud Selected Research

Neoplasms (Cancer)

12/2017Glutamine Addiction in Kidney Cancer Suppresses Oxidative Stress and Can Be Exploited for Real-Time Imaging.
10/2017Anticystogenic activity of a small molecule PAK4 inhibitor may be a novel treatment for autosomal dominant polycystic kidney disease.
10/2016Inhibiting tryptophan metabolism enhances interferon therapy in kidney cancer.
1/2016Dual and Specific Inhibition of NAMPT and PAK4 By KPT-9274 Decreases Kidney Cancer Growth.
6/2015PPARα inhibition modulates multiple reprogrammed metabolic pathways in kidney cancer and attenuates tumor growth.
1/2013Inhibition of PPARα induces cell cycle arrest and apoptosis, and synergizes with glycolysis inhibition in kidney cancer cells.
7/2012Kidney tumor biomarkers revealed by simultaneous multiple matrix metabolomics analysis.

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Omran Abu Aboud Research Topics

Disease

7Neoplasms (Cancer)
12/2017 - 07/2012
3Renal Cell Carcinoma (Grawitz Tumor)
12/2017 - 07/2012
3Kidney Neoplasms (Kidney Cancer)
12/2017 - 01/2016
1Autosomal Dominant Polycystic Kidney (ADPKD)
10/2017
1Ciliopathies
10/2017
1Lymphoma (Lymphomas)
01/2016

Drug/Important Bio-Agent (IBA)

2KPT-9274IBA
10/2017 - 01/2016
2NAD (NADH)IBA
10/2017 - 01/2016
2Tryptophan (L-Tryptophan)FDA Link
10/2016 - 07/2012
2EnzymesIBA
10/2016 - 01/2013
1CB-839IBA
12/2017
14-fluoroglutamineIBA
12/2017
1AntioxidantsIBA
12/2017
1Capsules (Microcapsules)IBA
12/2017
1Glutamine (L-Glutamine)FDA Link
12/2017
1Glutathione (Reduced Glutathione)IBA
12/2017
1Oxidants (Oxidizing Agents)IBA
12/2017
1Reactive Oxygen Species (Oxygen Radicals)IBA
12/2017
1Niacinamide (Nicotinamide)FDA LinkGeneric
10/2017
1TransferasesIBA
10/2017
1Protein Kinases (Protein Kinase)IBA
10/2017
1CateninsIBA
10/2017
1InterferonsIBA
10/2016
1methyl-thiohydantoin-tryptophanIBA
10/2016
1ThiohydantoinsIBA
10/2016
1KynurenineIBA
10/2016
1GW 6471IBA
06/2015
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
01/2013
1Proteins (Proteins, Gene)FDA Link
01/2013
1Transcription Factors (Transcription Factor)IBA
01/2013
1Biomarkers (Surrogate Marker)IBA
07/2012
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
07/2012

Therapy/Procedure

2Therapeutics
10/2017 - 10/2016